Wednesday, October 26, 2022

Epigenetic Conundrum

A disturbing possibility.

Genetics vs. epigenetics. To briefly summarize, genetics deals with the actual DNA sequences - the genome - while epigenetics deals with factors (e.g., DNA methylation, histone modifications, and other mechanisms cited in the linked article) that affect how the genetic information in the genome is expressed. Epigenetic changes can be heritable, at least for several generations (including being stable for a time after the environmental stimulus causing the epigenetic alteration is no longer present).

Readers of my work know that I prioritize genetics over epigenetics. After all, it are the DNA sequences, particularly the autosomal genome, that are the focus of ethnic genetic interests; further, genetics is the basic foundation of the phenotype, the fundamental instructions, the essential blueprint, while epigenetic influences are in the secondary role of modulating those basic instructions.

Having said that, secondary importance is still important. Epigenetics are important. In addition, they are typically more rapidly responsive to changes in the environment than are genetic mechanisms. So, whole both genetics and epigenetics can have crosstalk with the environment, when we focus on the environment influencing gene expression (in contrast to the opposite, the effects of gene expression on the environment, such as human culture), we observe that altering the genome is a slower process of selective pressure over generations, while epigenetic changes can occur in real time and then can be inherited by the subsequent generation(s). Therefore, epigenetic changes - the epigenome - are typically a more immediate response.

It is true that epigenetic inheritance eventually will – in the absence of continued environmental influences that caused the epigenetic changes to begin with – “peter out” over time, with the modifications being essentially “reset” via “reprogramming” to baseline (see the epigenetics and inheritance article linked above). That this can occur is itself underscores the importance of the environment, since epigenetic changes can be maintained over a long time period, and “reprogramming” avoided, if the environmental stimulus affecting the epigenome is continuously maintained.

A change in the environment can do two things – first remove the stimulus for a pre-existing epigenetic profile, allowing that profile to disappear over time via “reprogramming,” and, second, at the same time, it can produce a different epigenetic profile to come into existence. So, as stated above, while genetic changes are more important (and tend to be more long lasting) they are typically much slower to respond (however, see the mention of evolutionary capacitance below) while the epigenome can be reprogrammed within a single generation.

For example, if an environment of White Western Culture creates effects that manifest in a particular set of epigenetic changes, that epigenome will be maintained over very long time periods only insofar as that particular environment continues, and is able to maintain the “White Western” epigenome and the consequent gene expression and phenotype. If Jew-Colored influences result in a changed, non-Western multicultural environment, then White people can rapidly lose their pre-existing epigenome and have that replaced with a different epigenome reflecting non-White environmental influences. 

Thus, epigenetic changes in gene expression and White phenotype can occur and, at the same time, slower selective pressure will be at work to also alter the underlying fundamental genome as well.  The epigenetic changes may result in more subtle alterations in phenotype than the slower genetic changes; however, rapid subtle changes in the epigenome, multiplied over the masses of entire populations, can cause profound change to the character of the population and to the resulting society.  And this profound change can occur even if the change at the level of a single individual is more modest; thus, modest change multiplied over millions, tens of millions, and hundreds of millions of people can have a world historical impact.  

And then consider cross-talk and positive feedback loops.  A change in environment - caused, say, by the presence of alien peoples and cultures - causes a rapid epigenetic change in Whites.  Even if that change is modest, it can have profound effects on society – effects that cause further epigenetic changes and also exert even more selective pressure on the DNA gene sequences (genomes) themselves, etc. – with this constant “feed forward” mechanism amplifying over time. In this sense, multicultural diversity can be altering the very biological essence of Whiteness, and this process doesn’t even take into account the effects of miscegenation.

See this. So, not only can epigenetics explain phenotypic change that occurs more rapidly than expected from typical selection (and drift) genetic mechanism, but “evolutionary capacitance” also may play a role.

Different ethnies contain different types of, and levels, of such genetic variation; hence, human groups differ, qualitatively and quantitatively, in their evolutionary capacitance.  What this means in terms of a “racial soul” is that different groups may not reflect a type of phenotypic difference in one environment, but once exposed to a different, stressful environment, robustness breaks down and the inherent genetic variation is expressed in phenotypes previously masked.  This expression of masked phenotypes is one manifestation of the "racial soul."

Note that evolutionary capacitance can be epigenetic as well as genetic; the "stored variation" can result from genetic and/or epigenetic mechanisms. The bottom line here is that phenotypic change as a result of an altered environment can be more rapid than expected and this change can be heritable, or at least heritable to the extent that a particular environmental context is maintained. Phenotype equals genotype plus environment, and the environment can rapidly alter both epigenetics and evolutionary capacitance, as well alter the genome through slower processes of selective pressures. The rapid degeneration of Whites over the last several generations may in part be explained both by the more rapid mechanisms (epigenetics and evolutionary capacitance), as well as by the slower, more standard dysgenic effects acting at the level of the genome. In this way, degeneration may be due to dysgenics plus epigenetics plus evolutionary capacitance. Admixture can play a role as well, although this likely occurs to a greater extent once the original degeneration has set in and made the decayed race more susceptible to destructive practices such as miscegenation.

Therefore, not only are our racial enemies attacking us through all of the means we already know about and complain about, but they may be actually changing the very essence of our being. This is an existential attack against the meaning of White Being. The changed essence of Whiteness can alter how we engage in inclusive fitness and therefore directly affects defense of our ethnic genetic interests.

To secure our existence it is not enough to save the race and its genome but we must also place that race in an appropriate environment so that the racial genome and epigenome are properly manifested to secure White Being.

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