New Fst and Kinship Estimators

And a statement on Identity.

In all cases, emphasis added.

The abstract:

Kinship coefficients and FST, which measure genetic relatedness and the overall population structure, respectively, have important biomedical applications. However, existing estimators are only accurate under restrictive conditions that most natural population structures do not satisfy. We recently derived new kinship and FST estimators for arbitrary population structures [1, 2]. Our estimates on human datasets reveal a complex population structure driven by founder effects due to dispersal from Africa and admixture. Notably, our new approach estimates larger FST values of 26% for native worldwide human populations and 23% for admixed Hispanic individuals, whereas the existing approach estimates 9.8% and 2.6%, respectively. While previous work correctly measured FST between subpopulation pairs, our generalized FST measures genetic distances among all individuals and their most recent common ancestor (MRCA) population, revealing that genetic differentiation is greater than previously appreciated. This analysis demonstrates that estimating kinship and FST under more realistic assumptions is important for modern population genetic analysis.

I’m not a fan of Fst for genetic distance estimates for reasons discussed at this blog, and based on peer-reviewed literature, but it is used for that by many, so let’s see what this paper says.

From the main text:

However, the most commonly-used standard kinship estimator [9, 10, 13–19] is accurate only in the absence of population structure [2, 20]. Likewise, current FST estimators assume that individuals are partitioned into statistically-independent subpopulations [4, 5, 21–23], which does not hold for human and other complex population structures.

About Hispanics:

In particular, since differentiation increases from AFR to EUR to AMR (Fig. 3), the greatest kinship is between individuals with higher AMR ancestry, and the lowest kinship is between individuals with higher AFR ancestry (Fig. 4B and C).

So, it would seem that Hispanics like Mexicans and Peruvians have greater kinship among them than do the Caribbean-type Hispanics who stress Negro admixture to a greater extent.  Genetic differentiation (and kinship) seems highest among Amerindians and Pacific Islanders.

Fst between populations may be “substantially larger” than previously determined:

Remarkably, our estimated FST of 0.260 is substantially larger than estimates around 0.098 from existing approaches (Fig. 3) and previous measurements based on FST [30, 45] or related variance component models [31, 46, 47] — except for some AMOVA  ST estimates [48] (pairwise FST estimates [23, 49– 52] are not generally comparable to our estimate). Existing approaches underestimate FST because they assume zero kinship between subpopulations, clearly incorrect as seen in Fig. 1C, whereas our new approach models arbitrary kinship between individuals and leverages kinship to estimate FST.

Consistent with the “genes follow geography” paradigm, with genetic variation being both clinal and discontinuous.

We typically see that each ancestry cluster is concentrated in a certain geographical region, and this ancestry is also present to a lesser extent in neighboring regions and diminishes with geographical distance from its point of greatest concentration. This again argues for a complex population structure where relatedness at the population level falls on a continuum rather than taking on discrete values. The most notable geographic discontinuities in ancestry were observed for cluster 3, which is roughly West Eurasian ancestry.

And within West Eurasians?

Among West Eurasians, kinship is higher within Europe, reflecting another bottleneck.

So much for those that have denied any differences among West Eurasians.

It would be useful to use the new kinship estimator to get quantitative data for groups and transform those into child equivalents as well. That would be important for biopolitical considerations, an important component, but not the only component, of biopolitical identity. Identity – particularly from the general Yockeyian perspective I espouse – has multiple components.

Interestingly, he authors of this paper take a similar perspective; thus:

This partition into subpopulation is based on geography, history, language families, and our kinship estimates.

If “history” includes cultural/civilizational components, which are the major proximate interests, then this tracks well with my idea of Identity, composed both from the key ultimate interest (genetic kinship) and the major proximate interests. These different sets of interests synergize to form sharp discontinuities which are not present when only one interest is considered in isolation.

Now, I do not agree with the authors including the Ashkenazim in the European subpopulation, but that does not mean their approach is wrong – they are simply following the same simplistic mindset reflected by the testing companies that “they are found in Europe so they are European,” ignoring the history of the Ashkenazim as a Diaspora group akin to the Roma.

But, that’s a minor detail. The major approach of synergistic Identity is sound.

Reparations for White Americans, Endorsement Humiliations, and All the Rest

In der news.  In all cases, emphasis added.

Putting aside all the proximate issues of the costs of Colored crime, destruction of the cities, social welfare handouts, affirmative action, and the overall dispossession of Whites – which alone would be sufficient to guarantee White Americans huge reparations – there is a genetic, biological, EGI-based reparations imperative, as outlined here.

Genocide is worth reparations, is it not?  Genetic replacement is worth reparations, the lost child equivalents of EGI is definitely worth reparations. 

Reparations for White Americans.  Needed now more than ever.  Cash or check?

Tulsi Coconut – Princess of Negro Reparations, and her admirers.  And again.  And again.

“Our country is full.”  Yet is he on record saying he wants large amounts of more “legal” immigration.  Can Congress please impeach this buffoon, and vote to remove him from office?  Is it possible that all of the fat from the fast food he eats is clogging the arteries bringing blood to that underused spongy (small) mass that passes for his “brain?”

Remember that the great and good Desmond Jones claimed that Italy is, and shall remain, completely homogeneous to the end of time, forever and ever, amen.  Read this.

Said Mechaout, 27, born in Morocco but a naturalised Italian citizen, confessed to the killing, which occurred on the banks of the river Po in Turin on February 23rd, claiming he had purposely been waiting to kill a white Italian near his own age, Il Giornale reports.

“I hit a white, based on the obvious fact that a young Italian would have caused a sensation,” he allegedly told police. “I looked at him and I was sure he was Italian…

The wonderful racial theorists of Der Movement have told us that Italians and Moroccans are racially identical “Mediterraneans.” Interesting that Moroccans themselves do not believe that, and of course population genetics does not support that view either.  But, hey, the racial theorists are right because, well, they say so, and who can ever possibly argue against that?

Amren podcast.  The part about racial envy is true, but long time readers of this blog have read it all before.  See this from June 2015, which, by the way, was not the first time I had discussed that issue.  You’ll always get the breaking news and ideas here at EGI Notes first.

He’s better than Trump.

By the way, here is EGI Notes on October 5 2016:

For these reasons, I endorse Trump, even though I personally believe he is lazy and ignorant buffoon, an idiot with Jewish family connections, unread and unprepared, not very bright, hysterically undisciplined, a race cuck to the Negro – it is not Trump’s supporters who are the “basket of deplorables," it is instead Trump’s myriad personal flaws that instead constitute the basket. But remember what Yockey said about de Gaulle: Europe may be saved by an idiot. Similarly, America may be put on a better path – a path of despair, division, misery, hatred, and multicultural untenability – by the idiot Trump. 

My endorsement is made more difficult by the pitiful homoerotic pro-Trump hysteria in Der Movement. “Activists” – always eager for a “man on White horse” savior quick fix – have gravitated toward Trump (having abandoned Putin for the time being), and, also, the quota queens see in Trump a reflection of themselves.

From July 2016:

What's Der Movement going to do if and when Der Touchback publicly backpedals like a clown on a unicycle? 

What if he is elected and reneges on his promises?

Well now we know. They’ll pretend they never worshipped the man in a paroxysm of homoerotic sweaty fervor, and they’ll mutter “Javanka” and “I told you so.” Der Movement is full of the most outrageous gaslighting liars possible.  The only person who has the right to say “I told you so” is yours truly, the crazy and bitter swarthoid, that gesticulating Negroid, Ted Sallis. 

The fetishists on Counter-Currents assert that Italy is merely a “geographic expression.”  That tired old canard again.  The genetic evidence shows that Italians from different parts of that country have reasonably similar ancestry proportions, with the expected north-to-south clinal differences in gene frequencies matching the “genes mirror geography” paradigm.  There are no large, abrupt differences, just a shallow, expected cline.

Is Germany a geographic expression?  We’re not allowed to say that. It’s not in the “script.”